Best Home Vitiligo Treatment Protocol

Simple treatment protocol

A clear routine for supporting repigmentation

The routine combines controlled light exposure, topical support and daily nutritional support.

Protocol last updated: 1 August 2026

Important for children under 12 years: use Protopic 0.03% instead of Protopic 0.1%, and use Vitix Tablets instead of Vitistop Tablets. Prescription treatment should always be used according to the child’s doctor.

Your first month

A detailed day-by-day treatment example

Consistency is one of the most important parts of vitiligo treatment. The example below shows how tablets, topical treatment and three weekly light sessions can be organised during the first month.

The first-month routine

Vitistop Tablets: take 1 tablet after breakfast and 1 tablet after your evening meal. This initial two-tablet phase is intended to provide stronger nutritional support at the beginning of the routine, with the aim of supporting repigmentation and helping the body during an active phase of vitiligo.
Vitistop Gel: apply a thin layer to the white patches approximately 30 minutes before every 311 nm NB-UVB or controlled-sunlight session.
Protopic 0.1% or Opzelura: if either medicine has been prescribed, apply it approximately one hour before sleep. Add a morning application only if your doctor has advised it.
If you do not use Protopic or Opzelura: apply a thin layer of Vitistop Gel to the white patches at bedtime as part of your evening routine.
Light treatment: complete three sessions per week during the first two months, always leaving at least 48 hours between sessions.

Important: Protopic and Opzelura are prescription medicines. Use them only at the frequency and on the areas prescribed by your doctor. Do not apply them immediately before light exposure.

Example week: Monday to Sunday

Monday
Session 1

Morning

Take 1 Vitistop Tablet after breakfast.

Apply a morning dose of Protopic or Opzelura only if prescribed by your doctor.

Light treatment

Apply Vitistop Gel 30 minutes before treatment.

Use either a 311 nm NB-UVB lamp or controlled sunlight, but not both during the same session.

For an NB-UVB lamp, begin with the starting time specified in the device instructions or your individual treatment plan:

Adults: 30 seconds
Children: 15 seconds.

Evening

Take 1 Vitistop Tablet after your evening meal.

Apply prescribed Protopic or Opzelura approximately one hour before sleep. If you are not using either medicine, apply Vitistop Gel at bedtime.

Tuesday
Recovery day

Morning

Take 1 Vitistop Tablet after breakfast and check the reaction from Monday's session.

Light treatment

No light treatment.

Evening

Take 1 Vitistop Tablet after your evening meal.

Apply prescribed Protopic or Opzelura approximately one hour before sleep. If you are not using either medicine, apply Vitistop Gel at bedtime.

Wednesday
Session 2

Morning

Take 1 Vitistop Tablet after breakfast.

Light treatment

Apply Vitistop Gel 30 minutes before treatment.

If Monday caused no erythema and your NB-UVB device instructions permit time-based adjustment, increase the exposure by 20 seconds.

If the desired mild pinkness occurred, repeat the same exposure time. Treat only after the skin has recovered.

Evening

Take 1 Vitistop Tablet after your evening meal.

Continue the prescribed evening topical or apply Vitistop Gel at bedtime if no prescription topical is being used.

Thursday
Recovery day

Morning

Take 1 Vitistop Tablet after breakfast and assess Wednesday's skin reaction. The treated areas should appear slightly pink.

Light treatment

No light treatment.

Do not treat skin that is still red, irritated or not fully recovered.

Evening

Take 1 Vitistop Tablet after your evening meal and continue your usual evening topical routine.

Friday
Session 3

Morning

Take 1 Vitistop Tablet after breakfast.

Light treatment

Apply Vitistop Gel 30 minutes before treatment. Treat only once all pinkness or erythema from the previous session has fully subsided.

Use the reaction from Wednesday to select the exposure time. Increase NB-UVB exposure by 20 seconds only if no erythema occurred and your device instructions allow this adjustment.

Evening

Take 1 Vitistop Tablet after your evening meal.

Apply prescribed Protopic or Opzelura approximately one hour before sleep. If you are not using either medicine, apply Vitistop Gel at bedtime.

Saturday
Recovery day

Morning

Take 1 Vitistop Tablet after breakfast and check Friday's skin reaction.

Light treatment

No light treatment.

Allow the treated skin to recover completely.

Evening

Take 1 Vitistop Tablet after your evening meal and continue your evening topical routine.

Sunday
Routine day

Morning

Take 1 Vitistop Tablet after breakfast.

Light treatment

No light treatment.

Take photographs. Photographs taken every four weeks under similar lighting can make progress easier to recognise and can also help a healthcare professional assess the treatment response.

Evening

Take 1 Vitistop Tablet after your evening meal and continue your evening topical routine.

Weeks 2–4

Repeat the same Monday-Wednesday-Friday schedule throughout the first month. Continue taking two Vitistop Tablets daily, applying Vitistop Gel before every light session and following your prescribed topical routine.

Adjust each treated area according to its own response. Record the exposure time for every area and take comparison photographs at the end of week 4.

How the routine changes after the first month

Month 2

Reduce Vitistop Tablets to 1 tablet daily after a meal. Continue light treatment three times weekly, with at least 48 hours between sessions.

Month 3 onward

Continue with 1 Vitistop Tablet daily. Reduce light treatment to twice weekly and continue consistently until the end of the treatment process.

Tablet break

After every three months of tablet use, take a 3–4 week break from Vitistop Tablets before beginning the next cycle.

Home phototherapy

Preparing for your first NB-UVB session

Apply Vitistop Gel 30 minutes before the session.
Plug in the mains lead and switch the UVB unit on.
Initial exposure time (first session):
- Adults: 30 seconds
- Children: 15 seconds

Dose adjustment

Ongoing NB-UVB treatment directions

Treat 2–3 times per week, leaving at least 48 hours between UVB sessions.
Only treat when any redness (erythema) from the previous exposure has subsided and the skin has fully recovered.

A desired skin reaction (erythema - slight redness) typically appears 6–8 hours after UVB exposure:

No redness:

increase UVB exposure time by 20 seconds.

Mild redness:

if it clears within 24 hours, you may increase the exposure by 20 seconds at the next session.

Noticeable redness:

(desired response) if the skin is still slightly pink after 24 hours, keep the same exposure time and wait until the redness has completely faded before treating again.

Strong redness:

pause NB-UVB treatment until the skin has returned to normal, then reduce the exposure time by 20%.

The typical exposure per spot is about 3–4 minutes, depending on skin type.

Sunlight as an alternative – recommended in summer

Example routine with controlled sunlight

Apply Vitistop Gel to the affected areas and wait for approximately 30 minutes.
Expose the skin to sunlight for around 5 minutes.
If there is no mild redness by the following day, the exposure time may be increased gradually in steps of approximately 5 minutes.
Treat 2–3 times per week, leaving at least 48 hours between sessions.

Aim for a slight redness

A desired skin reaction is a slight redness (erythema). This mild, temporary pinkness may occur and can remain visible until the following day.

Typical exposure time

Because sunlight intensity varies depending on the season, the typical exposure time is roughly 15–30 minutes, depending heavily on your skin type and the strength of the sun. The exposure time should always be adjusted individually.

Real treatment progress

Results with Vitistop Gel and sunlight

The photographs below show visible progress on the hands, which are generally among the most difficult areas of the body to repigment. The customer followed a consistent routine using only Vitistop products together with controlled sunlight exposure.

Vitistop Gel and light treatment results on hands

Visible repigmentation progress on hands

“I am more than satisfied with the product. The improvement is clearly visible, and it has made me feel so much better emotionally. ❤️ Thanks to you, I no longer have to hide my hands under the table.” Marta

Additional note: The results might have been even better if the customer had used prescribed Protopic together with a 311 nm NB-UVB lamp during the winter months.

What to expect

Small dots of new pigment may begin to appear after approximately 4–8 weeks, but meaningful progress often requires several months of regular treatment.

Areas respond differently

The face, neck and body often respond more readily. Hands, fingers, feet and joints usually require more patience.

Need help building your routine?

Tell us the age of the person being treated, the location of the patches and whether you plan to use an NB-UVB lamp or sunlight.

Contact VitiligoShop

This guide provides general information only and does not replace diagnosis, medical advice or instructions supplied with an NB-UVB device or prescription medicine.

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