Vitiligo Treatment Protocol

A step-by-step guide developed in collaboration with dermatologists to help you work towards restoring your natural skin colour as effectively and safely as possible.

Dermatologist consultation

Treatment Guide for Adults (18+)

StepProductWhenHow to use
? Morning Vitistop Tablets Daily (after breakfast) Take 1 tablet with water.
? Evening Protopic 0.1% / Opzelura™* Daily (before bed) Apply a thin layer to vitiligo patches as directed by your doctor.
? Prep Vitistop Gel Treatment days (30 minutes before phototherapy) Massage gently into depigmented areas.
☀️ Therapy UVB lamp / sun 2–3 times per week Expose the skin until mild, pinkish redness appears.

*Protopic and Opzelura are prescription creams. Always consult your doctor.

Treatment Guide for Children (≤ 17 years)

StepProductWhenHow to use
? Morning Vitix Tablets Daily (after breakfast) Take 1 tablet with water.
? Evening Protopic 0.03% / Opzelura™** Daily (before bed) Apply a thin layer to vitiligo patches as directed by your doctor.
? Prep Vitistop Gel Treatment days (30 minutes before phototherapy) Massage gently into depigmented areas.
☀️ Therapy UVB lamp / sun 2–3 times per week Expose the skin until mild, pinkish redness appears.

**Opzelura is suitable for ages 12+ only. Always consult a paediatric dermatologist.

Phototherapy Guide

1. Preparation

Apply Vitistop Gel to depigmented areas and wait 30 minutes before light exposure.

Use either a UVB lamp or natural sunlight. Do not combine both on the same day.

2. Starting Exposure

UVB lamp:
Adults: start with 30 seconds
Children: start with 15 seconds

Sunlight:
Start with 5 minutes of direct sunlight on vitiligo patches.

3. Progression
  • No redness: increase exposure next session.
  • Mild pink redness (goal): keep the same time.
  • Strong redness: pause treatment until healed, then reduce time.

Sunlight rule: increase exposure by 5 minutes per session until mild, pinkish redness is achieved. Typical sunlight exposure is around 10–20 minutes, depending on skin type.

UVB lamp rule: increase exposure by 30 seconds per session until mild, pinkish redness is achieved. Typical exposure per area is around 3–4 minutes, depending on skin type.

Treatment goal: mild, pinkish redness (erythema) appearing 6–8 hours after exposure and fading within 24 hours. This indicates correct stimulation of pigment cells.

Perform phototherapy 2–3 times per week and always leave at least 48 hours between sessions.

Avoid Common Mistakes

  • ❌ Inconsistent phototherapy sessions.
  • ❌ Stopping treatment too early (before 3 months).
  • Incorrect UVB exposure times.
  • ❌ Incomplete regimen – skipping topical products or UVB light.

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*This article has been prepared in collaboration with a dermatologist and uses data from clinical studies presented at the EADV and AAD congresses (2019–2024).*

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