Vitiligo Treatment Protocol

This structured treatment protocol is built on practical experience, dermatological supervision, and established approaches to vitiligo therapy. Combining narrowband UVB phototherapy with targeted topical treatments and oral supplementation has proven highly effective in practice, offering the skin the best possible support during the repigmentation process.

Dr Michael Scheibenreif

Adult protocol (18+)

PhaseTreatment componentTimingPractical note
Morning Vitistop Tablets Daily after breakfast Take 1 tablet with water.
Evening Tacrolimus 0.1% ointment / Opzelura* Every evening before bed Apply a thin layer to the affected areas
Phototherapy Day Vitistop Gel 30 minutes before light exposure Gently massage into the depigmented areas
Phototherapy Day UVB Lamp (311 nm) / Sunlight 2–3 times a week Expose to light until a slight pinkish redness appears

Children and teenagers (under 18)

PhaseTreatment componentTimingPractical note
Morning Vitix Tablets Daily after breakfast Take 1 tablet with water.
Evening Protopic 0.03% Cream / Opzelura™ Cream** Every evening before bed Apply a thin layer to the affected areas
Phototherapy Day Vitistop Gel 30 minutes before light exposure Gently massage into the depigmented areas
Phototherapy Day UVB Lamp (311 nm) / Sunlight 2–3 times a week Expose to light until a slight pinkish redness appears

* In practice, Protopic 0.1% Cream and Opzelura™ Cream have a comparable frequency of use and efficacy.

** Opzelura™ is approved for use from the age of 12. For children under 12, please use only Protopic and consult the attending dermatologist regarding the dosage. Both Opzelura™ and Protopic® are available by prescription only.

NB-UVB phototherapy guide

1. Preparation

Apply Vitistop Gel to the depigmented areas and wait 30 minutes before exposure.

Use either a UVB lamp or natural sunlight as the light source for that day – not both.

2. Indicative starting exposure

Handheld NB-UVB lamp:
Adults often start at around 20–30 seconds
Children usually start lower, for example around 15 seconds

Natural sunlight:
A cautious starting point is often around 5 minutes of direct sunlight on the affected patches.

3. Gradual adjustment
  • No reaction: cautiously increase the exposure time by approximately 20 seconds at the next session.
  • Mild pink reaction: this is usually the desired response – keep the same exposure time.
  • Strong redness or burning: pause treatment until healed, then reduce the next exposure time.

Treatment goal: a mild pink reaction that appears around 6–8 hours after exposure and settles again within about 24 hours. This generally suggests that the dose is within the therapeutic range.

Average exposure times: typically around 3–4 minutes for the UVB lamp, and approximately 15–20 minutes for natural sunlight.

 

Carry out phototherapy 2–3 times per week and leave at least 48 hours between sessions.

Important safety points

  • Do not add strong sun exposure if you have already carried out NB-UVB treatment on the same day.
  • Pause treatment if strong redness, burning, blistering or prolonged irritation occurs.
  • Never increase exposure too abruptly, especially on thin or sensitive skin sites.
  • Check for photosensitising medicines if your skin reacts more strongly than expected.

Common pitfalls

  • Inconsistent phototherapy sessions — skip days and you lose momentum.
  • Stopping too early, often before a meaningful treatment duration (3+ months) has been reached.
  • Escalating exposure too quickly or without tracking the skin's pink response.
  • Irregular use of supportive topicals or internal vitamins.

Get started with our treatment bundles

Vitiligo support set

Repigmentation Support Set

Gel + Tablets

View set
Home NB-UVB support package

Home NB-UVB Support Package

UVB Lamp + Gel + Tablets

View package

Prefer to choose individual items?

If you are restocking or already know which part of the protocol you need, you can browse individual vitiligo care products separately.

8 items

  • Repigmentation Starter Kit (200ml Gel + 60 Tablets) £121 26%

    Most Popular Choice

    Repigmentation Starter Kit (200ml Gel + 60 Tablets)

    Vitistop Gel and Vitistop Tablets combine inside and outside support for vitiligo in one simple kit.

    In stock

    £89

    £121 Discount 26.4%

  • Most Popular Choice

    Vitistop Gel, 50 ml

    (1100050)

    Vitistop Gel 50 ml is a next-generation product developed specifically for vitiligo to help reduce white patches.

    In stock

    £40

  • Vitistop Gel, 100 ml £70 58%

    Sale

    Vitistop Gel, 100 ml

    (1100051)

    Vitistop Gel 100 ml is a next-generation product developed specifically for vitiligo to help reduce white patches.

    In stock

    £29

    £70 Discount 58.6%

  • Vitistop Gel, 200 ml

    (1100052)

    Vitistop Gel, 200 ml is a next-generation product developed specifically for vitiligo to help reduce white patches.

    In stock

    £99

  • Vitipro Gel - Extra Strong 50ml

    (1100200)

    Finally in stock! The most effective gel for depigmentation regulation and vitiligo management.

    In stock

    £45

  • Most Popular Choice

    Vitistop 60 - New Formula

    (1100022)

    Supports repigmentation in vitiligo and helps slow the progression of white patches.

    In stock

    £32

  • Vitix 30 tablets

    (1100020)

    A potent nutritional supplement featuring patented EXTRAMEL® technology. Combines primary and secondary antioxidants to neutralise oxidative stress and protect cells from free radical damage. Specifically formulated to support vitiligo management from within.

    In stock

    £20

  • Vitix Gel 50ml

    (1100010)

    The world's leading non-steroidal gel for vitiligo management. Utilising patented EXTRAMEL® microsphere technology, it helps regulate depigmentation by neutralising oxidative stress within the skin. Clinically proven to enhance results when combined with UVB phototherapy or controlled sun exposure.

    In stock

    £35

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